2025PRACTICE (AI optical diagnosis)Optical diagnosis & deskillingIn 895 adults undergoing colonoscopy with computer-aided detection and diagnosis, leaving optically non-neoplastic rectosigmoid polyps ≤5 mm in situ was non-inferior to resecting all detected polyps for adenoma detection rate.
2025Budzyń deskillingOptical diagnosis & deskillingIn 1,443 patients undergoing colonoscopy without AI assistance, three months of prior routine AI-assisted colonoscopy reduced the adenoma detection rate of later non-AI colonoscopy compared with the three months before AI was introduced.
2024Thiruvengadam CADeAdenoma detectionIn 1,100 patients undergoing colonoscopy in community practice, real-time computer-aided detection increased the adenoma detection rate compared with traditional colonoscopy.
2024COLO-DETECTAdenoma detectionIn 2,032 adults undergoing screening or symptomatic colonoscopy, computer-aided detection increased mean adenomas per procedure compared with standard colonoscopy.
2023Mangas-Sanjuan CADe (advanced neoplasia)Adenoma detectionIn 3,213 FIT-positive adults in a colorectal cancer screening programme, computer-aided polyp detection did not improve detection of advanced colorectal neoplasia compared with standard colonoscopy.
2022CADeT-CSMissed adenomasIn 232 patients undergoing screening or surveillance colonoscopy, CADe-assisted colonoscopy performed first reduced the adenoma miss rate at tandem colonoscopy compared with high-definition white-light colonoscopy performed first.
2022Wallace CADe (tandem)Missed adenomasIn 230 patients undergoing screening or surveillance colonoscopy, AI-assisted colonoscopy performed first reduced the adenoma miss rate at same-day tandem colonoscopy compared with standard colonoscopy performed first.
2020Repici CADeAdenoma detectionIn 685 adults undergoing screening, surveillance or diagnostic colonoscopy, real-time computer-aided detection increased the adenoma detection rate compared with high-definition colonoscopy without CADe.
2019Wang CADeAdenoma detectionIn 1,058 patients undergoing diagnostic colonoscopy, real-time deep-learning polyp detection increased the adenoma detection rate compared with standard colonoscopy.