2026AI-Echo RCTEchocardiographyIn 585 patients undergoing echocardiography, AI-based automatic measurement of echocardiographic parameters improved examination efficiency (time per patient and examinations per day) compared with manual measurement workflow.
2025TAILORED-AFRhythm & devicesIn 370 patients with drug-refractory persistent atrial fibrillation, AI-guided ablation of electrogram dispersion added to pulmonary vein isolation improved freedom from atrial fibrillation at 12 months compared with pulmonary vein isolation alone.
2024PROTEUSEchocardiographyIn 2,341 patients undergoing stress echocardiography, AI-augmented clinical decision-making did not show non-inferiority to standard clinical decision-making for appropriate referral for coronary angiography.
2023EchoNet-RCTEchocardiographyIn 3,495 echocardiograms undergoing quantification of cardiac function, initial AI assessment of left ventricular ejection fraction was non-inferior to initial sonographer assessment for the proportion of readings the cardiologist substantially changed, and superior.
2023NOTIFY-1CT & coronary physiologyIn 173 patients with incidental coronary artery calcium on a previous chest CT and no statin, deep-learning detection with notification of clinician and patient increased statin prescription within 6 months compared with usual care.
2023TARGET (CT-FFR)CT & coronary physiologyIn 1,216 patients with stable coronary disease and an intermediate stenosis on CT angiography, an on-site machine-learning CT-FFR care pathway reduced invasive angiography without obstructive disease or intervention within 90 days compared with standard care.
2023Ginder ML remote monitoringRhythm & devicesIn 2,413 patients with heart failure and an ICD or CRT-D, a neural network reading the 30 days of remote-monitoring data before device therapy improved prediction of appropriate ICD therapy for VT/VF compared with multivariable logistic regression.