Antifungal therapy
3 trials- 2022AMBITION-cmCryptococcal meningitisIn 844 adults with HIV-associated cryptococcal meningitis, a single 10 mg/kg dose of liposomal amphotericin B plus 14 days of flucytosine and fluconazole was non-inferior to 7 days of amphotericin B deoxycholate plus flucytosine for 10-week all-cause mortality.
- 2007Reboli (anidulafungin)CandidaemiaIn 245 patients with invasive candidiasis, anidulafungin was superior to fluconazole for global response at end of intravenous therapy.
- 2002Herbrecht (voriconazole)Invasive aspergillosisIn 277 patients with definite or probable invasive aspergillosis, voriconazole improved successful response and 12-week survival compared with amphotericin B deoxycholate.