Clostridioides difficile
3 trials- 2017MODIFY I/IIRecurrence preventionIn 2,655 patients receiving antibiotics for Clostridium difficile infection, a single dose of bezlotoxumab reduced recurrent CDI at 12 weeks compared with placebo.
- 2013van Nood FMTRecurrent CDIIn 43 patients with recurrent Clostridium difficile infection, faecal microbiota transplantation achieved cure more often than oral vancomycin.
- 2011Louie FidaxomicinInitial therapyIn 629 patients with Clostridium difficile infection, fidaxomicin reduced recurrence at 4 weeks compared with oral vancomycin with similar clinical cure.