2026Simonetto AI-ECG (cirrhosis)Implementation & new usesIn 15,596 adults having a routine ECG in primary care, an AI-ECG alert for advanced chronic liver disease increased new diagnoses of chronic liver disease with advanced fibrosis within 180 days compared with usual care.
2026TRICORDERHeart failure & cardiomyopathyIn 1.55 million patients registered at 205 primary care practices, an AI-enabled stethoscope in routine care did not improve detection of newly diagnosed heart failure over 12 months compared with routine care.
2026VITAL-AF (AI-ECG)Atrial fibrillationIn 16,937 primary care patients aged ≥65 years without known atrial fibrillation, single-lead ECG screening targeted by an AI-ECG risk model increased 2-year incident AF diagnosis compared with usual care in control practices.
2026Lin AI-ECG (potassium)Acute diagnosis & risk alertsIn 14,989 emergency department patients, a real-time AI-ECG alert for hyper- or hypokalaemia did not improve rates of hyperkalaemia- and hypokalaemia-related treatment within three hours compared with usual care without alerts.
2025DeepRhythmAIAtrial fibrillationIn 14,606 ambulatory ECG recordings annotated beat by beat, AI interpretation reported directly to the physician improved sensitivity for critical arrhythmias against cardiologist consensus panels compared with certified ECG technicians.
2025Liu AI-ECG (AF & anticoagulation)Atrial fibrillationIn 17,817 emergency and hospitalised patients treated by non-cardiologists, an AI-ECG atrial fibrillation alert to the treating physician increased NOAC prescription within 90 days of discharge compared with usual care.
2024Lin AI-ECG alertAcute diagnosis & risk alertsIn 15,965 hospitalised patients, an AI-ECG alert flagging those predicted to be at high risk of death reduced all-cause mortality within 90 days compared with usual care without the alert.
2024ARISE (AI-ECG)Acute diagnosis & risk alertsIn 43,234 patients presenting to the emergency department or admitted to hospital, AI-ECG interpretation with an automated STEMI alert to physicians reduced door-to-balloon time for STEMI compared with standard care.
2024Adedinsewo AI-ECG (peripartum cardiomyopathy)Heart failure & cardiomyopathyIn 1,232 pregnant and postpartum women in Nigeria, AI-guided screening with a digital stethoscope and AI-ECG improved identification of left ventricular systolic dysfunction compared with usual care.
2022Rushlow (EAGLE adoption)Implementation & new usesIn 11,573 patients whose clinicians received the AI-ECG low-EF alert, high clinician adoption of the alert increased diagnosis of low ejection fraction among AI-ECG-positive patients compared with low adoption of the alert.
2022BEAGLEAtrial fibrillationIn 1,003 patients with stroke risk factors and no known atrial fibrillation, AI-ECG risk stratification followed by ambulatory rhythm monitoring increased detection of new atrial fibrillation compared with propensity-matched usual care.
2021EAGLE (AI-ECG)Heart failure & cardiomyopathyIn 22,641 adults without known heart failure having a routine ECG, clinician access to an AI-ECG low-ejection-fraction prediction increased new diagnoses of low ejection fraction within 90 days compared with usual care without the AI result.