SoCRATES
Study of Cognitive Reality Alignment Therapy in Early Schizophrenia
Patient / Population Intervention / Exposition Comparaison Critère de jugement
In 315 first-episode psychosis patients, 5 weeks of CBT produced faster remission of auditory hallucinations and positive symptoms than supportive counselling or routine care.
N
315
Schéma
Multicentre RCT, UK
Critère
PANSS total/positive & PSYRATS over 70 days (acute phase)
Pertinence
2
RésultatNon-significant trends to faster improvement with CBT; faster resolution of auditory hallucinations vs supportive counselling (est −0.93, 95% CI −1.62 to −0.25, p=0.008), not maintained at 70 days.
Lewis S, et al. Br J Psychiatry. 2002;181(suppl 43):s91-s97. 10.1192/bjp.181.43.s91
Discussion et critique
Best evidence for early-CBT delivery in first-episode psychosis.