PARAMEDIC (LUCAS-2)
Pre-hospital Randomised Assessment of a Mechanical Compression Device in Cardiac Arrest
Paciente / Población Intervención / Exposición Comparación Desenlace
In 4,471 out-of-hospital cardiac arrests, LUCAS-2 mechanical chest compression did not improve 30-day survival versus manual CPR, and worsened functional outcome at 3 months.
N
4471
Diseño
Cluster-randomised RCT, UK ambulance services
Desenlace
30-day survival
Relevancia
3
Resultado6% vs 7% (adj. OR 0.86; 95% CI 0.64–1.15). CPC 1–2 at 3 months worse with LUCAS-2 (adj. OR 0.72).
Perkins GD, et al. Lancet. 2015;385(9972):947-955. 10.1016/S0140-6736(14)61886-9
Discusión y crítica
Mechanical CPR is not a routine replacement for high-quality manual CPR; reserve for transport, cath-lab and ECPR bridging.