PAMPer
Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock
Patient / Population Intervention / Exposition Vergleich Endpunkt
In 501 trauma patients at risk of haemorrhagic shock during HEMS transport, 2 units of prehospital thawed plasma reduced 30-day mortality versus standard care.
N
501
Design
Cluster-randomised RCT, US air ambulance
Endpunkt
30-day mortality
Relevanz
3
Ergebnis23.2% vs 33.0% (Δ −9.8; 95% CI −18.6 to −1.0; p=0.03; adj. HR 0.61).
Sperry JL, et al. N Engl J Med. 2018;379(4):315-326. 10.1056/NEJMoa1802345
Diskussion & Kritik
Supports prehospital plasma in helicopter EMS — implementation hinges on logistics.