DOREMI
Milrinone versus Dobutamine in Cardiogenic Shock
Doente / População Intervenção / Exposição Comparação Desfecho
In 192 patients with cardiogenic shock, milrinone produced similar rates of death and major complications compared with dobutamine.
N
192
Desenho
Double-blind RCT
Desfecho
Composite of death, resuscitated arrest, mechanical support and other events
Relevância
3
ResultadoNo significant difference between the two inotropes.
Mathew R, et al. N Engl J Med. 2021;385(6):516-525. 10.1056/NEJMoa2026845
Discussão e crítica
No winning inotrope in cardiogenic shock — the choice is by patient characteristics and side-effect profile, not outcomes.