DOREMI
Milrinone versus Dobutamine in Cardiogenic Shock
Paziente / Popolazione Intervento / Esposizione Confronto Esito
In 192 patients with cardiogenic shock, milrinone produced similar rates of death and major complications compared with dobutamine.
N
192
Disegno
Double-blind RCT
Esito
Composite of death, resuscitated arrest, mechanical support and other events
Rilevanza
3
RisultatoNo significant difference between the two inotropes.
Mathew R, et al. N Engl J Med. 2021;385(6):516-525. 10.1056/NEJMoa2026845
Discussione e critica
No winning inotrope in cardiogenic shock — the choice is by patient characteristics and side-effect profile, not outcomes.