TRISS
Transfusion Requirements in Septic Shock
Paziente / Popolazione Intervento / Esposizione Confronto Esito
In 998 patients with septic shock, transfusion threshold Hb 7 g/dL did not change 90-day mortality versus Hb 9 g/dL.
N
998
Disegno
Multicentre RCT, Scandinavia
Esito
90-day all-cause mortality
Rilevanza
2
Risultato43.0% vs 45.0% (RR 0.94; p=0.44).
Holst LB, et al. N Engl J Med. 2014;371(15):1381-1391. 10.1056/NEJMoa1406617
Discussione e critica
Extends the Hb 7 threshold to septic shock specifically.