TRILUMINATE
Transcatheter Repair for Patients with Tricuspid Regurgitation
Paziente / Popolazione Intervento / Esposizione Confronto Esito
In 350 patients with severe symptomatic tricuspid regurgitation, transcatheter tricuspid repair improved quality of life compared with medical therapy.
N
350
Disegno
RCT
Esito
Hierarchical composite (death, surgery, HF hospitalisation, quality of life)
Rilevanza
3
RisultatoWin ratio 1.48 — driven by quality of life; no reduction in death or HF hospitalisation.
Sorajja P, et al. N Engl J Med. 2023;388(20):1833-1842. 10.1056/NEJMoa2300525
Discussione e critica
Symptom benefit only — no hard-outcome signal yet. Whether quality-of-life improvement alone justifies the intervention is debated.