TOMAHAWK
Angiography after Out-of-Hospital Cardiac Arrest without ST-Segment Elevation
Paziente / Popolazione Intervento / Esposizione Confronto Esito
In 554 OHCA patients without ST-elevation, immediate angiography did not improve 30-day all-cause mortality versus delayed/selective strategy.
N
554
Disegno
Multicentre RCT, Germany/Denmark
Esito
30-day all-cause mortality
Rilevanza
3
Risultato54.0% vs 46.0% (HR 1.28; 95% CI 1.00–1.63; p=0.06) — numerically favouring delayed strategy.
Desch S, et al. N Engl J Med. 2021;385(27):2544-2553. 10.1056/NEJMoa2101909
Discussione e critica
Confirms COACT — also for non-shockable rhythms.