Sensky CBT
CBT vs Befriending in Treatment-Resistant Schizophrenia
Patient / Population Intervention / Exposure Comparison Outcome
In 90 patients with medication-resistant schizophrenia, 19 sessions of CBT produced more durable symptom improvement than a befriending control.
N
90
Design
RCT, UK
Endpoint
Positive/negative symptoms and depression (CPRS, SANS, MADRS)
Relevance
2
ResultAcute improvements equivalent; at 9-month follow-up only the CBT gains persisted.
Sensky T, et al. Arch Gen Psychiatry. 2000;57(2):165-172. 10.1001/archpsyc.57.2.165
Discussion & critique
Active control needed to test CBTp's specific effect; specific gains emerge over time.