SELECT2
Trial of Endovascular Thrombectomy for Large Ischemic Strokes
Patient / Population Intervention / Exposition Vergleich Endpunkt
In 352 patients with large ischaemic core (ASPECTS 3–5 or core ≥ 50 mL), endovascular thrombectomy improved the 90-day mRS distribution versus medical management.
N
352
Design
International multicentre RCT
Endpunkt
mRS shift at 90 days
Relevanz
2
ErgebnisGeneralised OR 1.51 (95% CI 1.20–1.89); mRS 0–2 20% vs 7%.
Sarraj A, et al. N Engl J Med. 2023;388(14):1259-1271. 10.1056/NEJMoa2214403
Diskussion & Kritik
With ANGEL-ASPECT extends thrombectomy to large infarct cores.