Schnurr PE

Prolonged Exposure in Female Veterans with PTSD

Paziente / Popolazione Intervento / Esposizione Confronto Esito

In 284 women veterans and active-duty soldiers with PTSD, 10 sessions of prolonged exposure produced higher loss of PTSD diagnosis than present-centered therapy.

284

Disegno

Multicentre RCT, VA, USA

Esito

PTSD symptom severity (post-treatment; assessed also at 3- and 6-month follow-up)

Rilevanza

RisultatoPE greater PTSD symptom reduction vs PCT (effect size 0.27, P=.03); no longer met PTSD criteria 41.0% vs 27.8% (OR 1.80, 95% CI 1.10-2.96, P=.01); effects consistent over time.

Schnurr PP, et al. JAMA. 2007;297(8):820-830. 10.1001/jama.297.8.820

Discussione e critica

Validated PE in a veteran cohort; cemented PE in the VA/DoD pathway.