PreVent
Bag-Mask Ventilation during Tracheal Intubation of Critically Ill Adults
Patient / Population Intervention / Exposition Vergleich Endpunkt
In 401 critically ill adults undergoing tracheal intubation, bag-mask ventilation between induction and laryngoscopy reduced severe hypoxaemia versus no ventilation.
N
401
Design
Multicentre RCT, US ICUs
Endpunkt
Lowest SpO₂ during intubation
Relevanz
3
ErgebnisMedian SpO₂ 96% vs 93% (Δ +3.9; p=0.01). Severe hypoxaemia (<80%) 10.9% vs 22.8%.
Casey JD, et al. N Engl J Med. 2019;380(9):811-821. 10.1056/NEJMoa1812405
Diskussion & Kritik
Broke the dogma of no bag-mask before intubation; aspiration risk did not rise.