PARTNER 1B
Placement of Aortic Transcatheter Valves — cohort B (inoperable)
Paciente / Población Intervención / Exposición Comparación Desenlace
In 358 patients with severe AS deemed inoperable, transcatheter aortic-valve replacement reduced all-cause mortality at 1 year compared with medical therapy.
N
358
Diseño
RCT, 1 yr
Desenlace
All-cause mortality
Relevancia
1
Resultado30.7 % vs 50.7 % (HR 0.55).
Leon MB, et al. N Engl J Med. 2010;363(17):1597-1607. 10.1056/NEJMoa1008232
Discusión y crítica
Vascular complications and stroke rates high in early TAVR — improved markedly in subsequent generations. Established TAVR for inoperable patients.