INCEPTION
Early ECPR for Refractory Out-of-Hospital Cardiac Arrest
Paziente / Popolazione Intervento / Esposizione Confronto Esito
In 160 patients with refractory OHCA, ECPR did not improve 30-day survival with favourable neurology versus conventional CPR.
N
160
Disegno
Multicentre RCT, Netherlands
Esito
30-day survival with CPC 1–2
Rilevanza
3
Risultato20% vs 16% (OR 1.4; 95% CI 0.5–3.5).
Suverein MM, et al. N Engl J Med. 2023;388(4):299-309. 10.1056/NEJMoa2204511
Discussione e critica
Real-world ECPR is hard to deliver fast enough across multiple centres; outcomes depend on system maturity.