IMPACT
Improving Mood with Psychoanalytic and Cognitive Therapies
Patient / Population Intervention / Exposure Comparison Outcome
In 470 adolescents with moderate-to-severe MDD, CBT, short-term psychoanalytic psychotherapy or brief psychosocial intervention produced equivalent 86-week response in head-to-head comparison.
N
470
Design
Pragmatic RCT, UK
Endpoint
MFQ depression at 86 weeks
Relevance
3
ResultAll three therapies equally effective; ~80% reached remission. No advantage of intensive over brief therapy.
Goodyer IM, et al. Lancet Psychiatry. 2017;4(2):109-119. 10.1016/S2215-0366(16)30378-9
Discussion & critique
Supports a brief-first stepped approach in adolescent depression; intensity is not the active ingredient.