HEMO

Hemodialysis (HEMO) Study

Patient / Population Intervention / Exposition Vergleich Endpunkt

In 1,846 haemodialysis patients, a higher dialysis dose and high-flux membranes did not reduce mortality compared with standard dose and low-flux membranes.

N
1.846
Design
2×2 factorial RCT
Endpunkt
All-cause mortality
Relevanz
2
ErgebnisHigh vs standard dose RR 0.96 (p=0.53); high- vs low-flux RR 0.92 (p=0.23).
Eknoyan G, et al. N Engl J Med. 2002;347(25):2010-2019. 10.1056/NEJMoa021583
Diskussion & Kritik

Set the minimum eKt/V at ~1.2; more dialysis is not better.