Foa EX/RP
Exposure and Response Prevention vs Clomipramine
Paciente / Población Intervención / Exposición Comparación Desenlace
In 122 adults with OCD, intensive exposure and response prevention achieved better response than clomipramine, their combination or pill placebo.
N
122
Diseño
4-arm RCT, USA
Desenlace
Y-BOCS response (CGI)
Relevancia
1
ResultadoResponse: EX/RP 62% ITT (86% completer); clomipramine 42% (48%); combination 70% (79%); placebo 8% (10%).
Foa EB, et al. Am J Psychiatry. 2005;162(1):151-161. 10.1176/appi.ajp.162.1.151
Discusión y crítica
Established EX/RP as the OCD first-line; combination did not exceed EX/RP alone.