FHN Daily
Frequent Hemodialysis Network Daily Trial
Paziente / Popolazione Intervento / Esposizione Confronto Esito
In 245 haemodialysis patients, six-times-weekly haemodialysis improved the composite of death or left-ventricular mass compared with conventional thrice-weekly dialysis.
N
245
Disegno
RCT
Esito
Composite of death or change in LV mass; death or physical-health score
Rilevanza
3
RisultatoHR 0.61 for the death/LV-mass composite (p=0.007).
FHN Trial Group. N Engl J Med. 2010;363(24):2287-2300. 10.1056/NEJMoa1001593
Discussione e critica
Frequent dialysis improves intermediate endpoints; the burden and vascular-access events temper routine use.