ESHOL
Estudio de Supervivencia de Hemodiafiltración On-Line
Patient / Population Intervention / Exposure Comparison Outcome
In 906 haemodialysis patients, online post-dilution haemodiafiltration reduced all-cause mortality compared with conventional haemodialysis.
N
906
Design
Open-label RCT
Endpoint
All-cause mortality
Relevance
3
Result30% lower risk of all-cause mortality; HR 0.70 (95% CI 0.53–0.92; p=0.01).
Maduell F, et al. J Am Soc Nephrol. 2013;24(3):487-497. 10.1681/ASN.2012080875
Discussion & critique
Hypothesis-generating for CONVINCE; the on-treatment analysis and convection-volume achievement complicate interpretation.