DahLIA
Dexmedetomidine for Agitated Delirium Preventing Extubation
Patient / Population Intervention / Exposition Vergleich Endpunkt
In 74 patients with agitated delirium preventing extubation, dexmedetomidine accelerated ventilator-free hours versus placebo.
N
74
Design
Multicentre RCT, ANZ
Endpunkt
Ventilator-free hours at 7 days
Relevanz
3
ErgebnisMedian ventilator-free hours 144.8 vs 127.5 (median diff +17.0 h, 95% CI 4.0–33.2; P=.01).
Reade MC, et al. JAMA. 2016;315(14):1460-1468. 10.1001/jama.2016.2707
Diskussion & Kritik
Niche but practice-changing: dex helps when delirium is the only obstacle to extubation.