COMPLETE
Complete vs Culprit-Only Revascularisation Strategies
Paziente / Popolazione Intervento / Esposizione Confronto Esito
In 4,041 STEMI patients with multivessel disease, staged complete revascularisation reduced CV death or MI compared with culprit-lesion-only PCI.
N
4041
Disegno
RCT, median 3 yr follow-up
Esito
CV death or new MI
Rilevanza
2
Risultato7.8 % vs 10.5 % (HR 0.74).
Mehta SR, et al. N Engl J Med. 2019;381(15):1411-1421. 10.1056/NEJMoa1907775
Discussione e critica
Settled a long-running debate. Timing (in-hospital vs ≤ 45 days post-discharge) was non-randomised — both strategies acceptable. Not powered for cardiogenic shock.