COMPLETE
Complete vs Culprit-Only Revascularisation Strategies
Patient / Population Intervention / Exposition Vergleich Endpunkt
In 4,041 STEMI patients with multivessel disease, staged complete revascularisation reduced CV death or MI compared with culprit-lesion-only PCI.
N
4.041
Design
RCT, median 3 yr follow-up
Endpunkt
CV death or new MI
Relevanz
2
Ergebnis7.8 % vs 10.5 % (HR 0.74).
Mehta SR, et al. N Engl J Med. 2019;381(15):1411-1421. 10.1056/NEJMoa1907775
Diskussion & Kritik
Settled a long-running debate. Timing (in-hospital vs ≤ 45 days post-discharge) was non-randomised — both strategies acceptable. Not powered for cardiogenic shock.