CARE-HF
Cardiac Resynchronisation in Heart Failure
Patient / Population Intervention / Exposition Vergleich Endpunkt
In 813 patients with heart failure and a wide QRS, cardiac resynchronisation therapy reduced death or unplanned cardiovascular hospitalisation compared with medical therapy.
N
813
Design
RCT
Endpunkt
Death or unplanned CV hospitalisation
Relevanz
1
Ergebnis39 % vs 55 %; all-cause mortality HR 0.64.
Cleland JGF, et al. N Engl J Med. 2005;352(15):1539-1549. 10.1056/NEJMoa050496
Diskussion & Kritik
Showed a mortality benefit from resynchronisation alone — the evidence base for CRT-P. The CRT-P versus CRT-D question remains individualised.