ASPIRED
Multi-centre open-label randomised controlled trial of immediate enhanced ambulatory ECG monitoring versus standard monitoring in acute unexplained syncope patients: the ASPIRED study
Patient / Population Intervention / Exposition Vergleich Endpunkt
In 2,234 emergency patients with unexplained syncope, immediate 14-day patch ECG monitoring was compared with standard care on self-reported syncope episodes at 1 year.
N
2.234
Design
UK multicentre, open-label, parallel-group randomised controlled trial; 1:1 web-based randomisation with allocation concealment, stratified by site; immediate 14-day ambulatory patch ECG monitor (BodyGuardian Mini, Preventice) fitted at emergency department/acute medical unit attendance plus standard care versus standard care alone; monthly self-report follow-up for 2 years; funded by the British Heart Foundation; sponsored by the University of Edinburgh and NHS Lothian (ACCORD); recruitment 2021–2026.
Endpunkt
Number of self-reported episodes of syncope at 1 year