ARREST
Advanced REperfusion Strategies for Refractory Cardiac Arrest
Paziente / Popolazione Intervento / Esposizione Confronto Esito
In 30 patients with refractory out-of-hospital VF arrest, ECPR plus expedited coronary angiography improved survival to hospital discharge versus standard ACLS.
N
30
Disegno
Single-centre RCT, Minnesota; stopped early
Esito
Survival to hospital discharge
Rilevanza
3
Risultato43% vs 7% (risk difference 36.2%, 95% CI 3.7–59.2; posterior probability of ECMO superiority 0.9861).
Yannopoulos D, et al. Lancet. 2020;396(10265):1807-1816. 10.1016/S0140-6736(20)32338-2
Discussione e critica
Tiny single-centre trial; benefit reflects an exceptionally organised ECPR system, not ECPR per se.