AMACING
A Maastricht Contrast-Induced Nephropathy Guideline
Patient / Population Intervention / Exposition Vergleich Endpunkt
In 660 patients with CKD undergoing contrast procedures, withholding prophylactic intravenous hydration was non-inferior for preventing contrast-associated AKI compared with hydration.
N
660
Design
RCT, non-inferiority
Endpunkt
Contrast-induced acute kidney injury
Relevanz
3
Ergebnis2.6% vs 2.7% (non-inferior); more complications in the hydration arm.
Nijssen EC, et al. Lancet. 2017;389(10076):1312-1322. 10.1016/S0140-6736(17)30057-0
Diskussion & Kritik
Questioned routine intravenous hydration in stable CKD with eGFR above 30.