TRICC
Transfusion Requirements in Critical Care
Patient / Population Intervention / Exposition Vergleich Endpunkt
In 838 euvolaemic ICU patients, a restrictive transfusion threshold of Hb 7 g/dL did not change 30-day mortality versus a liberal threshold of Hb 10 g/dL.
N
838
Design
Multicentre RCT, Canada
Endpunkt
30-day all-cause mortality
Relevanz
1
Ergebnis18.7% vs 23.3% (p=0.11); in-hospital 22.2% vs 28.1% (p=0.05).
Hébert PC, et al. N Engl J Med. 1999;340(6):409-417. 10.1056/NEJM199902113400601
Diskussion & Kritik
Established Hb 7 as the default ICU transfusion threshold for two decades.