STEP-BD Psy
Intensive Psychosocial Intervention in Bipolar Disorder
Patient / Population Intervention / Exposure Comparison Outcome
In 293 bipolar I/II patients in a depressive episode, intensive psychotherapy (FFT, CBT or IPSRT) improved 12-month recovery compared with 3-session collaborative care.
N
293
Design
Multicentre RCT, USA
Endpoint
Recovery from depression at 12 months
Relevance
2
ResultRecovery 64.4% vs 51.5% (p=0.01; HR 1.47). FFT, CBT and IPSRT equally effective.
Miklowitz DJ, et al. Arch Gen Psychiatry. 2007;64(4):419-426. 10.1001/archpsyc.64.4.419
Discussion & critique
Shows intensive psychotherapy speeds and deepens recovery from bipolar depression — but bona-fide modalities are interchangeable.