Skapinakis NMA
Network Meta-Analysis of OCD Treatments
Doente / População Intervenção / Exposição Comparação Desfecho
Across adults and children with OCD, psychological therapies (chiefly EX/RP) produced larger symptom reduction than each SSRI compared individually.
N
6652
Desenho
Network meta-analysis
Desfecho
Symptom severity (Y-BOCS)
Relevância
3
ResultadoIn children CBT > all SSRIs and most combinations; in adults psychotherapy ≥ pharmacotherapy.
Skapinakis P, et al. Lancet Psychiatry. 2016;3(8):730-739. 10.1016/S2215-0366(16)30069-4
Discussão e crítica
Network synthesis confirms EX/RP-first ordering, especially in paediatric OCD.