SETPOINT2
Early versus Standard Tracheostomy in Stroke
Paciente / Población Intervención / Exposición Comparación Desenlace
In 382 ventilated patients with severe stroke, early tracheostomy (≤4 days) did not improve 6-month functional outcome versus standard timing (7–10 days).
N
382
Diseño
Multicentre RCT, Germany/USA
Desenlace
Functional outcome (mRS 0–4) at 6 months
Relevancia
3
Resultado43.5% vs 47.1% (OR 0.93; p=0.73).
Bösel J, et al. JAMA. 2022;327(19):1899-1909. 10.1001/jama.2022.4798
Discusión y crítica
No advantage to rushing tracheostomy; the standard 7–10-day window is appropriate.