Safren ADHD
CBT Augmentation in Adults with ADHD on Medication
Patient / Population Intervention / Exposure Comparison Outcome
In 86 medication-treated adults with persistent ADHD, 12 sessions of CBT produced higher treatment response than relaxation with educational support.
N
86
Design
RCT, USA
Endpoint
Clinical Global Impression response
Relevance
2
ResultCBT 53% vs RES 23% (CGI ≤2); benefit persisted at 12 months.
Safren SA, et al. JAMA. 2010;304(8):875-880. 10.1001/jama.2010.1192
Discussion & critique
Anchor RCT for offering structured CBT alongside stimulant pharmacotherapy in adults.