REACT
DETECTion of the Prevalence of Silent Atherosclerosis Across Adult Life and Development of a Risk Calculator to Predict Its Presence — Phase I of the REACT (Early Cure of Atherosclerosis) Project
Patient / Population Intervention / Exposure Comparison Outcome
In 16,808 adults aged 18–70 years without known cardiovascular disease, whole-body imaging for atherosclerosis was studied for the age- and sex-specific prevalence of silent atherosclerosis.
N
16,808
Design
Prospective, observational, age- and sex-stratified imaging cohort in Denmark and Spain (4 sites each), multimodality screening at a baseline visit, follow-up planned to 2032
Endpoint
Prevalence of silent atherosclerosis, defined as atherosclerotic plaque in at least one examined territory (carotid, femoral or coronary), at the baseline imaging visit