POTS

Pediatric OCD Treatment Study

Paziente / Popolazione Intervento / Esposizione Confronto Esito

In 112 children and adolescents with OCD, CBT alone or combined with sertraline produced higher 12-week remission than sertraline or placebo alone.

112

Disegno

4-arm RCT, USA

Esito

CY-BOCS ≤10 remission at 12 weeks

Rilevanza

RisultatoCombination 53.6%, CBT 39.3%, sertraline 21.4%, placebo 3.6%.

POTS Team. JAMA. 2004;292(16):1969-1976. 10.1001/jama.292.16.1969

Discussione e critica

Made CBT first-line in paediatric OCD, with combination reserved for more severe cases.