NEXAF
The Norwegian Exercise in Atrial Fibrillation Trial
Patient / Population Intervention / Exposition Comparaison Critère de jugement
In 300 inactive adults with non-permanent atrial fibrillation, a 12-month supervised-then-home exercise programme was compared with usual care on AF burden and AF-specific quality of life at 12 months.
N
300
Schéma
multicentre (Trondheim, Bærum/Drammen, Tromsø), open-label, two-arm RCT; 1:1 supervised plus eHealth-based exercise vs usual care; blinded statistical analysis; 12-month follow-up with insertable cardiac monitor
Critère
co-primary: (1) total time in atrial fibrillation (burden, %) measured by insertable cardiac monitor over 12 months; (2) AFEQT overall score at 12 months