Morin Late-Life
CBT vs Temazepam for Late-Life Insomnia
Patient / Population Intervention / Exposure Comparison Outcome
In 78 older adults with chronic primary insomnia, CBT or temazepam (alone or in combination) reduced wake after sleep onset compared with pill placebo, with only CBT durable at 24 months.
N
78
Design
RCT, Canada
Endpoint
Polysomnographic and diary sleep measures
Relevance
2
ResultAcute: all active arms > placebo (WASO ↓54%); only CBT-I durable at 24-month follow-up.
Morin CM, et al. JAMA. 1999;281(11):991-999. 10.1001/jama.281.11.991
Discussion & critique
Defined the long-term advantage of CBT-I over hypnotics in older adults.