Lock FBT
Maudsley Family-Based Therapy for Adolescent Anorexia
Patient / Population Intervention / Exposure Comparison Outcome
In 121 adolescents with anorexia nervosa, Maudsley FBT produced higher 12-month full remission than adolescent-focused individual therapy.
N
121
Design
Two-site RCT, USA
Endpoint
Full remission (weight ≥95% expected, EDE within 1 SD)
Relevance
1
ResultAcute response similar; at 12 months FBT remission 49% vs AFT 23% (OR ~2.5).
Lock J, et al. Arch Gen Psychiatry. 2010;67(10):1025-1032. 10.1001/archgenpsychiatry.2010.128
Discussion & critique
Pivotal trial that made Maudsley FBT first-line for adolescent AN.