Lam CBT

Cognitive Therapy Adjunct in Bipolar Disorder

Paziente / Popolazione Intervento / Esposizione Confronto Esito

In 103 euthymic bipolar I patients, 14 sessions of cognitive therapy + treatment as usual reduced 12-month relapse compared with treatment as usual alone.

103

Disegno

RCT, UK

Esito

Bipolar relapse at 12 months

Rilevanza

RisultatoRelapse 44% (CBT) vs 75% (TAU); 30-month follow-up showed waning effect.

Lam DH, et al. Arch Gen Psychiatry. 2003;60(2):145-152. 10.1001/archpsyc.60.2.145

Discussione e critica

First clear demonstration of CBT relapse prevention in bipolar; effect attenuates and depends on early-course delivery.