Lam CBT
Cognitive Therapy Adjunct in Bipolar Disorder
Patient / Population Intervention / Exposition Vergleich Endpunkt
In 103 euthymic bipolar I patients, 14 sessions of cognitive therapy + treatment as usual reduced 12-month relapse compared with treatment as usual alone.
N
103
Design
RCT, UK
Endpunkt
Bipolar relapse at 12 months
Relevanz
3
ErgebnisRelapse 44% (CBT) vs 75% (TAU); 30-month follow-up showed waning effect.
Lam DH, et al. Arch Gen Psychiatry. 2003;60(2):145-152. 10.1001/archpsyc.60.2.145
Diskussion & Kritik
First clear demonstration of CBT relapse prevention in bipolar; effect attenuates and depends on early-course delivery.