INTERACT-3
Care Bundle for Acute Intracerebral Haemorrhage
Paciente / Población Intervención / Exposición Comparación Desenlace
In 7,036 patients with acute ICH across 121 hospitals, a bundle of BP, glucose, temperature and anticoagulation reversal improved functional outcome at 6 months versus usual care.
N
7036
Diseño
Cluster-randomised stepped-wedge trial
Desenlace
mRS at 6 months
Relevancia
2
ResultadoCommon OR for better outcome 0.86 (95% CI 0.76–0.97).
Ma L, et al. Lancet. 2023;402(10395):27-40. 10.1016/S0140-6736(23)00806-1
Discusión y crítica
Largest ICH trial; supports a coordinated bundle rather than chasing single targets.