IDEAL-AF
Individually DEsigned Ablation of Low-voltage areas in patients with persistent Atrial Fibrillation — a randomised controlled multicentre trial
Doente / População Intervenção / Exposição Comparação Desfecho
In 200 patients with persistent atrial fibrillation and low-voltage areas, pulmonary vein isolation plus individualised low-voltage ablation was compared with pulmonary vein isolation alone on freedom from atrial arrhythmia at 12 months.
N
200
Desenho
multicentre (5 Swedish ablation centres), patient-blinded RCT; 1:1 PVI plus low-voltage-zone ablation vs PVI alone; 90-day blanking; 12-month primary endpoint with smartphone ECG monitoring and Holter at 3 and 12 months; 2-year follow-up
Desfecho
freedom from documented atrial arrhythmia (AF or AT) lasting >30 s off antiarrhythmic drugs at 12 months after one to two ablation procedures within 6 months