Heimberg CBGT
Cognitive-Behavioural Group Therapy vs Phenelzine
Patient / Population Intervention / Exposure Comparison Outcome
In 133 adults with social phobia, phenelzine or CBGT achieved better response than pill placebo or educational-supportive therapy.
N
133
Design
Multicentre RCT, USA
Endpoint
Clinical Global Impression response
Relevance
2
ResultAt 12 wk both phenelzine (77%) and CBGT (75%) response rates superior to pill-placebo (41%) and educational-supportive therapy (35%); χ²=16.14, P<.001. Phenelzine superior to CBGT on several measures (larger effect sizes).
Heimberg RG, et al. Arch Gen Psychiatry. 1998;55(12):1133-1141. 10.1001/archpsyc.55.12.1133
Discussion & critique
Classic acute-vs-durable contrast; informed staged combination strategies in social phobia.