DanGer Shock

Microaxial Flow Pump in Infarct-Related Cardiogenic Shock

Paziente / Popolazione Intervento / Esposizione Confronto Esito

In 360 patients with STEMI-related cardiogenic shock, a microaxial flow pump (Impella CP) reduced 180-day all-cause mortality compared with standard care.

360

Disegno

RCT, 180-day follow-up

Esito

All-cause mortality at 180 days

Rilevanza

Risultato45.8 % vs 58.5 % (HR 0.74, NNT 8). More severe bleeding, limb ischaemia, haemolysis and renal failure.

Møller JE, et al. N Engl J Med. 2024;390(15):1382-1393. 10.1056/NEJMoa2312572

Discussione e critica

First positive mechanical-support RCT in AMI cardiogenic shock, but strict selection (STEMI, no prolonged-resuscitation arrest). ACC/AHA 2024 class IIa. Complications are frequent — patient selection is everything.