Alcohol-use disorders: diagnosis, assessment and management of harmful drinking (high-risk drinking) and alcohol dependence (NICE guideline CG115)
CG115 pairs a psychological core with an adjunctive pharmacological one: after assisted withdrawal, harmful drinking and mild dependence are treated with a psychological intervention focused on alcohol — cognitive behavioural therapy, behavioural therapies or social network and environment-based therapy — and moderate to severe dependence adds acamprosate or oral naltrexone alongside that therapy. The register trials below cover the behavioural evidence base and the combined pharmacological-behavioural comparison.
Esta norma cita 2 dos 62 ensaios marcantes do nosso registo de Psiquiatria e psicoterapia.
Psychological interventions for alcohol misuse1
- 1997Project MATCHPsiquiatria · PUS · ÁlcoolEm 1.726 adultos com perturbação por uso de álcool, TCC, terapia de aumento motivacional ou facilitação dos 12 passos (12 semanas) obtiveram outcomes de consumo de álcool equivalentes ao longo de um seguimento de 1 ano.
Combined pharmacological & behavioural treatment1
- 2006COMBINEPsiquiatria · PUS · ÁlcoolEm 1.383 adultos com dependência alcoólica, a gestão médica mais naltrexona ou intervenção comportamental combinada reduziram os dias de consumo intensivo relativamente a placebo ou acamprosato, sem efeito aditivo.