Alcohol-use disorders: diagnosis, assessment and management of harmful drinking (high-risk drinking) and alcohol dependence (NICE guideline CG115)
CG115 pairs a psychological core with an adjunctive pharmacological one: after assisted withdrawal, harmful drinking and mild dependence are treated with a psychological intervention focused on alcohol — cognitive behavioural therapy, behavioural therapies or social network and environment-based therapy — and moderate to severe dependence adds acamprosate or oral naltrexone alongside that therapy. The register trials below cover the behavioural evidence base and the combined pharmacological-behavioural comparison.
Questa linea guida cita 2 dei 62 studi fondamentali del nostro registro di Psichiatria e psicoterapia.
Psychological interventions for alcohol misuse1
- 1997Project MATCHPsichiatria · DUS · AlcolIn 1.726 adulti con disturbo da uso di alcol, TCC, Motivational Enhancement Therapy o Twelve-Step Facilitation (12 settimane) hanno ottenuto outcome sul comportamento di consumo alcolico equivalenti nell'arco di un follow-up di 1 anno.
Combined pharmacological & behavioural treatment1
- 2006COMBINEPsichiatria · DUS · AlcolIn 1.383 adulti con dipendenza da alcol, il medical management più naltrexone o intervento comportamentale combinato ha ridotto i giorni di consumo elevato rispetto a placebo o acamprosato, senza effetto additivo.