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ESC 2024 Hypertension

2024 ESC Guidelines for the management of elevated blood pressure and hypertension

The 2024 ESC Guidelines introduce an 'elevated blood pressure' category and a general systolic target of 120–129 mmHg, spanning measurement, drug therapy, device treatment and cardiovascular prevention. This page maps the landmark trials from our register that the guideline cites — grouped by theme.

This guideline cites 7 of the 199 landmark trials in our Cardiology register.

Source
McEvoy JW, McCarthy CP, et al. Eur Heart J. 2024;45(38):3912–4018. · European Heart Journal
Read the full guideline ↗

Blood-pressure targets & intensive lowering2

  • 2015SPRINTCardiology · HTN · BP targetSystolic Blood Pressure Intervention Trial
  • 2008HYVETCardiology · HTN · ElderlyHypertension in the Very Elderly Trial

Drug therapy & combinations2

  • 2015PATHWAY-2Cardiology · HTN · MRAPrevention And Treatment of Hypertension With Algorithm-based therapY-2
  • 2002ALLHATCardiology · HTN · Drug classAntihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Renal denervation (device therapy)2

  • 2023SPYRAL HTN-ON MEDCardiology · HTN · Renal denervationRenal Denervation With the Symplicity Spyral System in Uncontrolled Hypertension on Antihypertensive Medications (pivotal/Expansion cohort)
  • 2014SYMPLICITY HTN-3Cardiology · HTN · Renal denervationRenal Denervation in Patients with Resistant Hypertension

Cardiovascular prevention1

  • 2000HOPECardiology · Coronary · ACE inhibitorHeart Outcomes Prevention Evaluation